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March 15, 2023
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Top in endocrinology: Metabolically healthy obesity; FDA clears CGM sensors

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The percentage of adults with metabolically healthy obesity has increased over the past 2 decades, from 3.2% in 1999-2002 to 6.6% in 2015-2018, recent data show.

According to An Pan, PhD, a professor in the department of epidemiology and biostatistics in the School of Public Health at Tongji Medical College, Huazhong University of Science and Technology, in China, “effective strategies are needed to optimize metabolic status among individuals with obesity to prevent cardiovascular and metabolic comorbidities.”

Sign outside FDA HQ in Washington, DC.
The FDA has cleared the FreeStyle Libre 2 and FreeStyle Libre 3 for integration with automated insulin delivery systems for people with diabetes. Image: Adobe Stock

It was the top story in endocrinology last week.

The second top story covered the FDA’s clearance of a pair of integrated continuous glucose monitoring sensors for automated insulin delivery systems.

Read these and more top stories in endocrinology below:

Prevalence of metabolically healthy obesity increasing in US, but remains low overall

The percentage of adults with metabolically healthy obesity increased from 1999 to 2018 but remains much smaller than the proportion of those with metabolically unhealthy obesity, according to study data. Read more.

FDA clears two CGM sensors for integration with automated insulin delivery systems

The FDA has granted clearance to allow two integrated continuous glucose monitoring sensors to be used with automated insulin delivery systems, according to an industry press release. Read more.

Nearly 50% of adults with obesity have hypertension, increased mortality risk

About half of all adults with obesity have controlled or uncontrolled hypertension and a significantly higher mortality rate compared with normotensive counterparts, researchers reported in Obesity. Read more.

Irregular sleep and visceral obesity linked to high BP for adolescents

Visceral adipose tissue plus circadian misalignment — delayed and irregular sleep midpoints — is associated with increased blood pressure among adolescents, according to a study published in Hypertension. Read more.

Metformin exposure in utero not linked to higher BMI for children of women with diabetes

Children of women with type 2 diabetes who took 1,000 mg metformin twice daily during pregnancy had a similar BMI z score at age 2 years compared with those of women using placebo, according to study data. Read more.