Top in endocrinology: Type 1 diabetes drug approval; hedonic hunger

Last week, the FDA announced that it has approved Tzield to delay the onset of type 1 diabetes in adults and children aged 8 years and older with stage 2 type 1 diabetes.

According to the agency, Tzield (teplizumab-mzwv, Provention Bio) injection “may deactivate the immune cells that attack insulin-producing cells, while increasing the proportion of cells that help moderate the immune response.” It was the top story in endocrinology last week.

Another top story was about new trial data that showed weight loss reduced hedonic hunger and bariatric surgery reduced food cravings. The study authors noted that future research should examine the long-term impact of diet-induced weight loss and bariatric surgery on hedonic hunger.

Read these and more top stories in endocrinology below:

FDA approves teplizumab to delay type 1 diabetes onset

The FDA has approved teplizumab to delay the onset of type 1 diabetes for both adults and children aged 8 years and older with stage 2 type 1 diabetes, according to an agency press release. Read more.

Weight loss reduces hedonic hunger, bariatric surgery lowers food cravings

Weight loss reduced hedonic hunger independently of modality, and bariatric surgery resulted in several beneficial changes in food reward and preferences, according to trial data published in Obesity. Read more.

Nighttime outdoor artificial light may increase type 2 diabetes risk

Chronic exposure to outdoor artificial light at night was associated with increased glucose levels, HbA1c and insulin resistance, according to study findings published in Diabetologia. Read more.

Low-carbohydrate diet improves glycemia for adults with elevated HbA1c, prediabetes

A low-carbohydrate dietary intervention resulted in improved glycemia for adults with elevated HbA1c who were not on glucose-lowering medications, according to trial results published in JAMA Network Open. Read more.

Updated NIH guideline makes more people eligible for bariatric, metabolic surgery

Updates to the 1991 NIH statement on gastrointestinal surgery for severe obesity include recommendations for metabolic and bariatric surgery, BMI threshold adjustments and consideration of surgery for children and adolescents. Read more.