Top in endocrinology: Acute cholecystitis; bone fragility measurement tool
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Data from the FDA Adverse Reporting System revealed an association between the use of GLP-1 receptor agonists and the onset of acute cholecystitis.
Researchers found 36 cases of acute cholecystitis that were linked to GLP-1 receptor agonists, which led to serious outcomes like the development of pancreatitis, liver necrosis and even death. It was the top story in endocrinology last week.
Another top story was the FDA’s device designation for a bone fragility measurement tool for older women. The clinical tool is being used to identify women aged older than 70 years who are at risk for fracture and allows those patients to receive treatment to prevent fragility fractures.
Read these and more top stories in endocrinology below:
Cases of acute cholecystitis linked to GLP-1 receptor agonist use in US
Researchers have found 36 cases of acute cholecystitis associated with the use of GLP-1 receptor agonists in the U.S., according to findings from the FDA Adverse Event Reporting System published in JAMA Internal Medicine. Read more.
Tool for measuring bone fragility in older women receives breakthrough device designation
The FDA has granted breakthrough device designation to a clinical tool for determining bone fragility and fracture risk for older women, according to an industry press release. Read more.
Skeletal muscle mass loss linked to cognitive decline in older adults with type 2 diabetes
Decreases in skeletal muscle mass are associated with cognitive decline in type 2 diabetes, particularly among older adults, according to a study published in Journal of Diabetes and Its Complications. Read more.
Total infections in infancy more significant than antibiotic use for childhood obesity
The number of infections in the first year of life was significantly associated with childhood obesity and was a stronger risk factor than antibiotic use, according to study data. Read more.
Children with overweight, obesity may lack readiness for kindergarten
Among a group of Canadian children in year 2 of kindergarten, those with overweight or obesity were twice as likely to be unready for school as their peers with normal weight, according to study data. Read more.