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July 28, 2021
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Top in endocrinology: Romosozumab vs. alendronate, health effects of shift work

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Data showed that 1 year of romosozumab followed by a year of alendronate was associated with larger gains in bone mineral density at the lumbar spine than 2 years of alendronate alone in postmenopausal women with osteoporosis.

A report on the data was the top story in endocrinology last week.

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Another top story highlighted research on the health effects of shift work outside of a normal daytime schedule. Compared to non-shift work, researchers reported that two-shift and three-shift work increased the risk for metabolic syndrome among adults.

Read these and more top stories in endocrinology below:

Greater lumbar spine BMD, bone strength gains with romosozumab for postmenopausal women

Postmenopausal women with osteoporosis receiving romosozumab-aqqg (Evenity, Amgen) for 12 months had larger improvements in bone mineral density and bone strength at the lumbar spine compared with those receiving alendronate alone, according to study data. Read more.

Shift work outside of normal daytime hours increases risk for metabolic syndrome

Adults employed in shift work outside of a normal daytime schedule have a greater risk for metabolic syndrome, according to findings published in Nutrition, Metabolism and Cardiovascular Diseases. Read more.

FDA approves once-weekly exenatide for children with type 2 diabetes

AstraZeneca announced that the FDA approved its GLP-1 receptor agonist exenatide for children aged 10 to 17 years with type 2 diabetes, the first once-weekly injectable approved for pediatric use in the United States. Read more.

Shared risk factors may drive cognitive decline and bone loss, fracture risk for women

There is a bidirectional relationship between cognitive decline and accelerated bone loss with increased fracture risk among women, according to new data published in the Journal of Bone and Mineral Research. Read more.

Connectivity, digital tools becoming the ‘sixth vital sign’ in health care

Determining someone’s digital health connectivity may be just as important as measuring their BP, pulse or body temperature, according to experts. Read more.