Top in hem/onc: Early puberty and breast cancer, incomplete pregnancy and ovarian cancer

A longitudinal study revealed the mechanism of early puberty as a driver of breast cancer risk. It was the top story in hematology/oncology last week.

Another top story was about a study that demonstrated an association between incomplete pregnancies and a reduced risk for ovarian cancer.

Read these and more top stories in hematology/oncology below:

Longitudinal study reveals mechanism of early puberty as a driver of breast cancer risk

Early onset of puberty and other pubertal parameters have been linked to a significantly increased risk for developing breast cancer later in life. The mechanism of this association was the focus of a longitudinal study conducted by researchers at Cincinnati Children’s Hospital Medical Center and University of Cincinnati. Read more.

Incomplete pregnancies linked to reduced risk for ovarian cancer

Incomplete pregnancies appeared to be associated with a reduced risk for invasive epithelial ovarian cancer, according to results of a study published in Journal of the National Cancer Institute. Read more.

Pediatric cancer survivors often face endocrine, cardiometabolic issues later in life

Children with cancer are particularly vulnerable to the adverse effects of treatments such as chemotherapy, radiation and hematopoietic stem cell transplantation. However, some treatment effects may not become apparent until years later. Read more.

FDA grants priority review to Tagrisso for lung cancer subset

The FDA has granted priority review to osimertinib (Tagrisso, AstraZeneca) for adjuvant treatment of certain patients with early-stage non-small cell lung cancer. Read more.

Overuse of antibiotics may shorten survival in urothelial carcinoma

The overprescribing and overuse of antibiotics has been scrutinized in recent years due to the threat of antimicrobial resistance. Research has suggested that up to 50% of antibiotics used in cancer treatments are prescribed inappropriately. Read more.