Gastrointestinal Conditions News

A 2022 outbreak of unexplained acute severe hepatitis in children has been linked to a strain of adeno-associated virus 2, supporting the theory that disease pathogenesis results from viral coinfection, according to data reported in Nature.

Prenatal exposure in the 1960s and ’70s to dicyclomine, a component of the anti-nausea drug Bendectin, increased the risk for colorectal cancer in adult offspring, according to data reported in JNCI Cancer Spectrum.

Since April 2022, more than 1,300 children in 35 countries have developed acute severe hepatitis of unknown etiology, with the United States and the United Kingdom accounting for 65% of global cases, according to recent WHO data.

The FDA has agreed on Abivax’s initial pediatric study plan for the development of obefazimod in children aged 2 to 17 years with inflammatory bowel disease, the company announced in a press release.

Disorders of gut-brain interaction cause symptoms throughout the digestive tract including pain, changes in bowel patterns, nausea, regurgitation or vomiting, which can be upsetting or embarrassing for children and teens

CHARLOTTE, N.C. — Exposure to ustekinumab and vedolizumab during pregnancy did not increase maternal and fetal complications, and researchers recommend continued use in pregnant mothers with inflammatory bowel disease.

The 35th annual Infectious Diseases in Children Symposium will be held Nov. 19 and 20 in New York.

The bacterium Clostridioides difficile tends to “cooperate” with microorganisms in the gastrointestinal tract, such as the pathogen Enterococcus, which can help the bacterium thrive, according to a study published in Nature.

WASHINGTON — Although adenovirus infection has been widely implicated in an outbreak of acute, severe hepatitis in children, data presented at The Liver Meeting found no “singular definitive etiology” for these cases.

In this Healio video, Andrew J. Costandi, MD, MMM, details the Enhanced Recovery After Liver Transplantation protocol at Children’s Hospital Los Angeles, which shortened post-transplant ICU stays from 7 to 3 days in pediatric patients.