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Gastrointestinal Conditions News
Use of nonbiopsy ESPGHAN criteria depends on celiac serology test performance
A recent guideline published by the European Society of Paediatric Gastroenterology, Hepatology and Nutrition, or ESPGHAN, which established criteria for omitting a diagnostic biopsy for pediatric celiac disease, has a high positive predicted value dependent on the performance of celiac serology tests, according to research data.
HBV found to mature infant immune systems
Hepatitis B virus exposure in utero boosted immune system maturation among a cohort of neonates born to HBV-positive mothers in a Singapore-led study, according to newly published data in Nature Communications.
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Children with autism found more likely to have gastrointestinal symptoms
Children with autism spectrum disorder are more likely to have gastrointestinal symptoms as infants and toddlers compared with children with typical development; and more likely to have constipation compared with children with developmental delays, according to data published in JAMA Psychiatry.
Slow IBD diagnosis in children leads to more advanced disease
Slow diagnosis of inflammatory bowel disease in pediatric patients was associated with advanced bowel involvement at the time of diagnosis, according to recent data.
FMT induces remission in pediatric patients with Crohn's disease
Children with Crohn’s disease achieved remission after fecal microbiota transplant, recent study data found.
Growth monitoring could lead to earlier detection of celiac disease
Most children with detected persistent transglutaminase autoantibodies were asymptomatic and had normal growth by age 4 years, according to study findings in Pediatrics.
Statewide universal vaccine policy reduced rotavirus strains, hospitalizations
MEMPHIS, Tenn. — Implementation of a universal pentavalent rotavirus vaccine in Rhode Island significantly reduced the number of rotavirus-associated hospitalizations and strains of rotavirus circulating in the community, according to data presented at the St. Jude/PIDS Pediatric Infectious Diseases Research Conference.
Racial disparities exist among children with Crohn's disease
Disparities in hospital readmissions, complications and procedures in pediatric Crohn’s disease patients are related to race, according to data from a recent retrospective review.
Celiac disease prevalence more than doubled in US since 1988
The overall prevalence of celiac disease in the United States has increased between 1988 and 2012 and is more common in whites, whereas blacks are more likely to adopt a gluten-free diet without a diagnosis of celiac disease, according to data from a recent population-based, cross-sectional study.
Altered microbiome may lead to liver disease in patients with cystic fibrosis
Intestinal lesions were prevalent in adolescents and young adults with cystic fibrosis and cirrhosis and associated with altered fecal microbiome and slower small bowel transit time, according to recently published data.