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Gastrointestinal Conditions News
Thalomid induces, maintains remission in refractory pediatric UC
Results from a pilot randomized controlled trial showed Thalomid induced and maintained clinical remission in children and adolescents with ulcerative colitis refractory or intolerant to other immunosuppressives.
Childhood physical, sexual abuse associated with increased risk for developing ulcerative colitis
Adults who were physically or sexually abused during childhood had an estimated twofold increased risk for developing ulcerative colitis, according to data from a Canadian population-based study.
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TDF therapy in pregnancy reduces HBV DNA, risk of vertical transmission
Viremic mothers treated with tenofovir disoproxil fumarate during pregnancy had decreased hepatitis B virus infection DNA levels in their blood, which reduced the infection’s DNA serum levels in infants at birth and reduced overall mother-to-child transmission, according to study data.
Cephalosporin use increases risk for pediatric C.difficile-associated diarrhea
A recent study found that the risk for community-associated cases of Clostridium difficile-associated diarrhea in pediatric patients may be increased by the use of cephalosporin and gastrointestinal feeding tubes.
Unsedated transnasal endoscopy effective, lower-cost for monitoring pediatric EoE
Unsedated transnasal endoscopy was shown to be a safe, well-tolerated and lower-cost alternative to esophagogastroduodenoscopy for evaluating pediatric eosinophilic esophagitis, according to recent study data.
Most recreational water-based outbreaks caused by Cryptosporidium
Data show that Cryptosporidium, a chlorine-tolerant parasite, causes the majority of waterborne outbreaks of illness in treated recreational water, according to a recent study published in MMWR.
ESPGHAN: More research needed on use of biosimilars in pediatric IBD
Children with inflammatory bowel disease who are responding well to biologics should not be switched to biosimilars until more research data becomes available, according to an expert consensus statement from the European Society for Pediatric Gastroenterology, Hepatology and Nutrition.
Rise in popularity of backyard poultry increases Salmonella risk
It is estimated that Salmonella causes 1.2 million illnesses, 23,000 hospitalizations and 450 deaths annually in the United States, according to the CDC.
Mortality risk greater in children with severe C. difficile, chronic conditions
Certain chronic comorbidities and more severe infection were associated with a higher mortality risk among children with Clostridium difficile infection, according to recent data.
Infant mortality, morbidity similar for ampicillin-susceptible, ampicillin-resistant E. coli
Data from a recent study showed there were no clinically relevant differences in mortality and morbidity among infant patients diagnosed with blood stream infections caused by either ampicillin-susceptible or ampicillin-resistant Escherichia coli.