Gastrointestinal Conditions News

Children with inherited liver disease who underwent liver transplantation for hepatocellular carcinoma had superior long-term survival compared with children without inherited liver disease and adults with inherited liver disease, according to a recently published study.

In patients with inflammatory bowel disease, diet significantly impacts the fecal microbiome, which is believed to be involved in triggering and maintaining inflammation. In particular, diets high in sugar and fat have been implicated in the pathogenesis of IBD.

The number of suspected and confirmed cholera cases in war-torn Yemen is nearing 1 million, while suspected cases of diphtheria there have surpassed 2,000, according to WHO.

Seres Therapeutics announced the FDA has given its microbiome drug candidate SER-287 Orphan Drug Designation for the treatment of pediatric ulcerative colitis.

A 2016 outbreak of Shiga toxin producing Escherichia coli has been attributed to raw flour from one American-based flour producer, according to findings published in The New England Journal of Medicine.

The CDC issued another warning about raw milk, saying people who consumed products from a company called Udder Milk should see their doctor because of potential contamination with a dangerous pathogen that can cause miscarriage and other complications in pregnant women and severe illness in people with weakened immune systems.

According to WHO, Vibrio cholerae causes 1.3 to 4 million infections and 21,000 to 143,000 deaths worldwide each year. The disease incidence and severity disproportionately affect children aged younger than 5 years. Cholera is spread by water or food contaminated with human feces from a person with active cholera or from a person who is convalescing from cholera or has had asymptomatic or mildly symptomatic cholera. Following cholera infection, excretion of the organism can last for at least 2 weeks. Estimates of the ratio of asymptomatic to symptomatic people range from 3:1 to more than 100:1. The bacterium can also survive in the environment in brackish rivers and coastal waters for long periods.

ORLANDO — In this exclusive video from Advances in IBD 2017, David Suskind, MD, professor of pediatrics and director of clinical gastroenterology at Seattle Children’s Hospital, University of Washington, discusses recent advances in the use of nutrition therapy in pediatric inflammatory bowel disease.

Alanine aminostransferase maintained better levels at mid-childhood when children took in a higher amount of the alpha-tocopherol isoform of vitamin E at early childhood, according to data published in Hepatology.

ORLANDO, Fla. — A child’s diagnosis with inflammatory bowel disease affects not only the patient, but the parents as well, and those parents, especially “helicopter parents,” should not be forgotten when managing the patient’s care, according to presenters at Advances in IBD 2017.