Gastrointestinal Conditions News

Albireo Pharma Inc. received a rare pediatric disease designation from the FDA for its lead product candidate A4250, an ileal bile acid transporter inhibitor designed for the treatment of progressive familial intrahepatic cholestasis, according to a company press release.

ATLANTA — There is a risk that the pathogens that accumulate on kitchen towels can cause food poisoning, but how much of a risk depends on several factors, including family size, diet type and what exactly the towels are used for, researchers reported here.

WASHINGTON — Results of a prospective longitudinal analysis showed that the incidence of gastroesophageal variceal hemorrhage in children with biliary atresia was lower than previously described, and that gastroesophageal variceal hemorrhage was more common in patients with features of portal hypertension, according to a presentation at Digestive Disease Week 2018.

WASHINGTON, D.C. — Oral iron supplementation during infancy and diphtheria and polio vaccination appeared to reduce the risk for developing inflammatory bowel disease later in life, according to a presenter here.

Incorporation of age-based diagnostic recommendations into electronic medical records for children with acute liver failure reduced indeterminant diagnoses and may improve outcomes by reducing liver transplantation rates without an increase in mortality, according to a recently published study.

Pediatric patients with chronic hepatitis B and immune-tolerant characteristics who underwent interferon therapy followed by treatment with Epivir had significantly improved the rates of undetectable serum HBV DNA, HBV e-antigen seroconversion and HBV surface antigen loss compared with control, according to a recently published study.

Two major vaccination campaigns have been implemented since January as part of the global effort to reduce cholera by 90% by 2030, according to WHO.

Albireo enrolled the first patient in a phase 3 clinical trial for its lead product candidate A4250, an ileal bile acid transporter inhibitor designed to treat pediatric patients with progressive familial intrahepatic cholestasis, according to a press release.

Hotel pools are a frequent source of recreational waterborne disease, causing 32% of all swimming-related disease outbreaks in the United States, according to new research published today by the CDC.

Oral administration of ginger was safe and effective for treating vomiting in children with acute gastroenteritis, according to new research presented at the ESPGHAN annual meeting.