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Endocrinology News
No link between vitamin D status, offspring bone mineral content
Previous studies have suggested that vitamin D deficiencies among children can lead to risk for fracture and other comorbidities. However, researchers from the United Kingdom have demonstrated that there is no relevant link between maternal vitamin D status in pregnancy and offspring bone mineral content in late childhood.
No link between vitamin D status, offspring bone mineral content
Previous studies have suggested that vitamin D deficiencies among children can lead to risk for fracture and other comorbidities. However, researchers from the United Kingdom have demonstrated that there is no relevant link between maternal vitamin D status in pregnancy and offspring bone mineral content in late childhood.
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Closed-loop system reduced hypoglycemia, improved glycemic control
Patients with type 1 diabetes experienced significant improvements in overnight glucose control and nocturnal hypoglycemic events with use of an artificial pancreas, or closed-loop delivery system, compared with standard pump therapy, according to researchers.
FDA halts pediatric clinical trials of Sensipar following death
The FDA has stopped all pediatric clinical trials of cinacalcet hydrochloride following the death of a pediatric patient (aged 14 years) in a trial, according to a press release on the agency’s website today.
Early mortality among young adults linked to cardiometabolic risk factors
Among those aged 12 to 39 years, smoking, adiposity and hyperglycemia were associated with an overall increased risk for mortality before aged 55 years, whereas elevated blood pressure was linked to an increased risk for mortality from endogenous causes.
Firstborns may be at higher risk for metabolic, CV diseases
Researchers in New Zealand suggest that firstborn children are at a greater risk for developing metabolic or cardiovascular diseases later in life, according to data published in the Journal of Clinical Endocrinology & Metabolism.
Hospital admittance failed to improve HbA1c in adolescents
QUEBEC CITY — Elective hospital admission for adolescents with inadequately controlled type 1 diabetes is not an effective means to improve HbA1c values, according to 12-month data presented here at the Canadian Pediatric Endocrine Group 2013 Scientific Meeting.
GLP-1 therapy shows promise for severely obese adolescents
Despite recent FDA approvals for the adult population, obesity therapies for adolescents are limited. However, preliminary data from a 3-month trial examining the effects of a glucagon-like peptide-1 receptor agonist on BMI in severely obese adolescents have yielded positive findings.
Canadian initiative plans to standardize pediatric reference intervals
QUEBEC CITY — The establishment of reference values is vital to detecting and monitoring disease, and the Canadian Laboratory Initiative on Pediatric Reference Intervals, known as CALIPER, aims to establish a reference values database of pediatric disease biomarkers.
Genetic sequencing appears key to personalized medicine in pediatrics
QUEBEC CITY — Modern genomics in the form of next-generation sequencing and exome sequencing will be commonplace in the Canadian pediatric endocrine clinic in the near future, according to presenter Kym Boycott, PhD, MD, FRCPC, FCCMG.