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Baked milk diet well-tolerated by some children with milk allergies

Issue: April 2014

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SAN DIEGO — Most children with milk allergy can safely tolerate a diet that includes foods with baked milk, according to data presented here at the 2014 American Academy of Allergy, Asthma and Immunology Annual Meeting.

In addition, most children tolerated unheated milk by the end of the study follow-up, according to Anna H. Nowak-Wegrzyn, MD, of the Icahn School of Medicine at Mount Sinai in New York City, and colleagues.

The researchers assessed the status of children’s milk allergies up to 106 months after baseline (median= 83 months). Children in the study ingested one to three servings of baked milk daily. Follow-up included an unheated milk food challenge and a telephone interview to determine milk allergy status.

Of 52 children who initially tolerated baked milk, 37 (72%) became tolerant of unheated milk, 10 children (19%) continued to consume baked milk only, and five children (9%) avoided all forms of milk.

Of 38 participants with no milk restrictions, two (5%) developed eosinophilic esophagitis two reported exercise-induced symptoms following milk intake, and five children experienced mild oral symptoms after consuming liquid milk.

Researchers did not find significant differences between final tolerance outcomes and initial immunologic limitations of children who tolerated baked milk.

Of the 23 children in the study who reacted to baked milk at the time they were enrolled in the study, 18 (78%) avoided all forms of milk and three children began to tolerate baked milk; two tolerated unheated milk by the end of the study, according to the researchers.

The researchers concluded that a “baked milk diet is safe and well tolerated in the vast majority of baked milk-tolerant children, in contrast to the milk oral immunotherapy.”

For more information:

Nowak-Wegrzyn AH. Abstract 372. Presented at: AAAAI 2014; Feb. 28- March 4, 2014; San Diego.

Disclosure: The researchers report no relevant financial disclosures.