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Asthma during pregnancy increased disease risk in offspring
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Asthma during pregnancy increases the risk of various offspring diseases, according to recent study findings published in Pediatrics.
“These findings together with the high prevalence of maternal asthma during pregnancy, make it important to further put a focus on follow-up time extended beyond the perinatal period and to cover a larger spectrum of offspring diseases,” researchers wrote.
The study included 66,712 mother-child pairs, 4,145 of which reported having asthma during pregnancy.
Researchers found that asthma during pregnancy increased the offspring’s risk of infectious and parasitic diseases (HR=1.34; 95% CI, 1.23-1.46); endocrine and metabolic disorders (HR
=1.26; 95% CI, 1.02-1.55); diseases of the nervous system (HR=1.43; 95% CI, 1.18-1.73), ear (HR=1.33; 95% CI, 1.19-1.48), respiratory system (HR=1.43; 95% CI, 1.34-1.52), digestive system (HR=1.17; 95% CI, 1.04-1.32), and skin (HR=1.39; 95% CI, 1.20-1.60); and malformations (OR=1.13; 95% CI, 1.01-1.26). However, when P values were adjusted asthma during pregnancy no longer put offspring at risk for endocrine and metabolic diseases and diseases of the digestive system.
“Our findings that offspring of mothers suffering from asthma during pregnancy are at increased risk for a variety of diseases during childhood suggests that careful monitoring of the asthmatic pregnant woman and her developing fetus and child are highly warranted, regardless of the causes for this association,” researchers wrote.
Disclosure: See study for a full list of disclosures.
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