Osteoporosis News

The current evidence on the beneficial balance of vitamin D and calcium supplementation for fracture prevention in adults is lacking, according to a new US Preventive Services Task Force recommendation statement.

A comparison study of balloon kyphoplasty and KIVA, a vertebral augmentation device, used in 168 patients with osteoporotic vertebral body fractures showed both techniques significantly restored anterior, posterior and midline vertebral body height ratios.

Upon further analysis of data from the FREEDOM trial, researchers confirmed that denosumab significantly improved radius bone mineral density, mass and strength compared with placebo, besides significantly reducing the risk for wrist fracture.

Results from a phase 3 trial of an investigational cathepsin inhibitor suggest improved overall proximal femoral strength due to increasing trabecular bone mineral density and endosteal bone apposition at the femoral neck in postmenopausal women.

Improvements in the quality of care of osteoporosis and effective cost savings occurred when pragmatic and inexpensive interventions were directed toward patients with incidental vertebral fractures and their physicians, according to this study.

WHO fracture risk algorithm scores with or without bone mineral density were useful models to predict clinical fractures in obese and nonobese women, according to data published in the Journal of Bone and Mineral Research.

The risk for fracture appeared to decrease for more than 1 year after a single infusion of zoledronic acid, according to data from a post hoc analysis of two studies.

Not enough eligible women are being screened and treated for osteoporosis in the primary care setting, a recent study suggests. Additionally, black women were less likely to be screened compared with white women.

The link between depression, anxiety, smoking and lower BMD in adults has been established. In a recent study, researchers suggest that adolescent girls who smoked and experienced depressive symptoms could also experience less bone mass accrual.

Previous studies have established that one of the major adverse effects of steroid use is glucocorticoid-induced osteoporosis. In a recent study published in Spine, researchers have suggested that postmenopausal women who were administered a single epidural steroid injection as treatment for back pain adversely experienced significant BMD loss of the hip.