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Osteoporosis News
Denosumab/teriparatide superior to either treatment alone
BALTIMORE —Combined denosumab and teriparatide demonstrated superior efficacy compared with either treatment alone for patients at high risk for fractures, according to data presented at ASBMR 2013.
Increased inflammatory markers point toward higher risk for hip fracture
BALTIMORE — Higher concentrations of inflammatory factors were associated with higher risk for hip fracture, according to study results presented here.
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FREEDOM extension: Denosumab continued to improve BMD, prevent fractures
BALTIMORE — The initial reports from the extension of the FREEDOM trial show continued efficacy of denosumab for increasing bone mineral density and prevention of fracture in patients receiving the drug in the long term and those switched over from placebo treatment.
Patients with osteoporosis have low rate of mechanical failure after distal radial fracture surgery
SAN FRANCISCO — Researchers found a low risk of mechanical failure in patients with osteoporosis who had distal radius fracture fixation with a volar locking plate, according to a presenter here.
Calcium plus vitamin D modestly reduced fracture risk
BALTIMORE — In a meta-analysis of randomized, controlled trials, calcium plus vitamin D only modestly reduced fracture risk and was not associated with increased risk for cardiovascular disease outcomes, according to data presented by Jacqueline R. Center, MBBS, PhD, FRACP, at ASBMR 2013.
Muscle power, force associated with cortical bone strength
BALTIMORE — Muscle power and force could contribute to cortical bone strength via distinct mechanisms, according to data presented by Sarah A. Hardcastle, MBChB, BSc, MRCP, clinical research fellow at the University of Bristol in the United Kingdom, here at ASBMR 2013.
Risk for fracture tripled in men with sarcopenia and osteopenia/osteoporosis
BALTIMORE — Men with sarcopenia and osteopenia/osteoporosis had a threefold greater risk for fracture compared with men who only had one of the diseases, according to data presented at ASBMR 2013.
Trabecular bone score may improve prediction power for osteoporotic fractures in postmenopausal women
The use of trabecular bone scores improved the performance of lumbar spine areal bone mineral density in the prediction of vertebral osteoporotic fractures in postmenopausal women, according to this study.
Pain-related exams may help diagnose recent osteoporotic vertebral compression fractures
Researchers from Rome who evaluated elderly patients at an outpatient spine clinic found examining these patients’ pain-related behavior clinically could predict the presence of an osteoporotic vertebral compression fracture, according to results of this study.
Repeat BMD test every 2 years may be unnecessary
Conducting a bone mineral density screening every 2 years to quantify fracture risk may not be necessary in adults aged at least 75 years who have not been treated for osteoporosis, according to recent data.
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