Infection News

Findings from a retrospective analysis suggested that the use of a rapid musculoskeletal diagnostic panel, or MDP, could have shortened the time it took to identify the cause of infection, provide appropriate antibiotics and reduce the length of stay for children.

Researchers suggested that diabetic foot osteomyelitis — which results in worse outcomes compared with soft tissue infections — should be separated into its own category in the Infectious Diseases Society of America’s diabetic foot classification system to better guide treatment and improve outcomes.

White blood cell counts and inflammatory markers may hold lower diagnostic utility among patients in an immunosuppressed state who experienced periprosthetic joint infection after total joint arthroplasty, according to published research.

LISBON, Portugal — In this exclusive video from the EFORT Annual Congress, Javad Parvizi, MD, FRCS, summarizes his Erwin Morscher Honorary Lecture where he discussed recent advances in periprosthetic joint infection. Parvizi said solving periprosthetic joint infection may involve biomarkers and next generation sequencing as well as a clinical picture that includes the biome of the patient.

Use of white blood cell/bone marrow single-photon emission CT with standard CT for diagnosis of chronic infection in failed shoulder arthroplasty yielded low negative predictive values, high positive predictive values and poor accuracy, according to published results.

In patients with pelvic endoprostheses affected by infection following tumor resection, infections were mostly polymicrobial flora, caused by gram-negative microorganisms and may be correlated with intestinal flora, according to recently published results.

LISBON, Portugal — The evolution that is underway within periprosthetic joint infection will depend on better understanding the current and future roles of microbiomes, immune modulation, genetic science and biofilm disruption in regard to this problem, according to Javad Parvizi, MD, FRCS.

The FDA announced marketing authorization of the Synovasure Lateral Flow Test Kit by CD Diagnostics Inc. to help detect periprosthetic joint infection in the synovial fluid of patients who are assessed for revision surgery. Data on the kit were reviewed through the de novo premarket review pathway.

Irrigation and debridement correlated with a higher failure rate in patients with an acute hematogenous periprosthetic joint infection than in patients with an acute postsurgical periprosthetic joint infection, according to recently published results.

Results published in the European Journal of Epidemiology showed one-stage revision total hip replacement to treat periprosthetic joint infection was as effective as two-stage THR revision performed for this indication.