Biologics News

Researchers at Northwestern University are among the first to design a bioactive nanomaterial that promotes new cartilage growth in vivo without using added growth factors. The minimally invasive therapy activates bone marrow stem cells to produce natural cartilage, according to research published online in the Proceedings of the National Academy of Sciences.

The FDA has granted approval for the marketing of collagenase clostridium histolyticum, a biologic product indicated for the treatment of Dupuytren’s contracture in adult patients with a palpable cord.

Treating the immune system of patients with complex regional pain syndrome leads to a significant reduction in pain, according to researchers with the University of Liverpool.

Acetaminophen administered after severe muscle injuries in a rat model prevented oxidative kidney damage and failure, according to a recent study in the Proceedings of the National Academy of Sciences.

Surgeons at Cincinnati Children’s Hospital Medical Center have performed a new procedure that combines adipose-derived stem cells, bone morphogenic proteins and allograft surrounded by a vascularized periosteal sleeve to grow new cheek bones in a 14-year-old patient with Treacher Collins syndrome.

Collaborations between investigators at the National Institutes of Health and other U.S. institutions has led to the discovery of the third gene in a sequence that accounts for previously unexplained forms of osteogenesis imperfecta.

After nearly a decade of increases, funding for biomedical research is beginning to decline in the United States, study findings published in the Journal of the American Medical Association indicated.

A clinical Round Table discussion on the role of platelet-rich plasma in connective tissue repair was the most read article appearing in Orthopedics Today and on the ORTHOSuperSite.com in 2009.

Findings from an analysis of the Women’s Health Initiative showed that women taking oral bisphosphonates for osteoporosis were less likely to develop invasive breast cancer.

Surgeons are finding success using a bone marrow aspirate concentration procedure for patients with early-stage avascular necrosis of the hip.