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Biologics News
Experts publicly debate on- and off-label use of BMPs at Medicare coverage meeting
Health and medical professionals comprising the Medicare Evidence Development & Coverage Advisory Committee of the Centers for Medicare & Medicaid Services met September 22 to consider the available evidence about using bone morphogenetic proteins clinically in on- and off-label applications.
Researchers identify molecular gatekeeper of arthritis
The elimination of a key protein – referred to as a “molecular gatekeeper” – leads to the development of arthritis in mice, according to a study published in the Journal of Experimental Medicine.
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Study finds PRP injection more beneficial than corticosteroid injection for chronic lateral epicondylitis
A platelet-rich plasma injection reduced pain and increased function significantly more than a corticosteroid injection in patients with chronic lateral epicondylitis, according to a double-blind, randomized controlled trial with 1-year follow-up.
PRP shows promise, well-designed studies needed before conclusions can be made
The search for a minimally invasive solution to improve tissue repair is highly desirable. The use of platelet-rich plasma is a simple and minimally invasive way to obtain a natural concentration of autologous growth factors and apply them to a lesion site to improve healing in tissues with low healing potential.
No positive effect on bone health from soy isoflavones seen in randomized trial
Researchers at the University California-Davis, Iowa State University and centers, who conducted the longest study of its kind into the role that soy isoflavones play in the health of postmenopausal women, found only a slight benefit when the target population used this natural compound, according to a United Stated Department of Agriculture-Research, Education, and Economics press release.
Intra-articular lubricin injections could prevent osteoarthritis following ACL injury
Injection of intra-articular lubricin following an ACL injury may reduce cartilage degeneration and the development of post-traumatic osteoarthritis, according to researchers from Rhode Island Hospital.
Promising initial results seen with bone graft substitute using carbon nanotubes
Trials with a new porous biodegradable compound showed it satisfactorily regenerated bone during in vitro and in vivo experiments, according to a researcher at the Health Unit of Tecnalia at the University of Basque Country in Spain.
‘Cell homing’ technique could grow natural joints for orthopedic patients
A proof-of-concept study has shown that natural joints can be grown using a host’s own stem cells; the technique could one day be applied to orthopedic patients undergoing joint replacement surgery, according to a Lancet press release.
Breakdown of bone keeps blood sugar in check, study finds
The destruction of old bone during normal skeletal regrowth plays an important role in regulating blood sugar, according to researchers with Columbia University Medical Center.
Osteocyte spindles responsible for sensing mechanical stimulation, signaling bone growth
Investigators from Texas have discovered a key factor in the process of bone remodeling and report that their findings could possibly lead to new treatments for osteoporosis, osteoarthritis and age-related bone loss.