Biologics News

Device maker ReGen Biologics took exception to the plans by the FDA’s Center for Devices and Radiological Health (CDRH) to rescind 510(k) clearance for Menaflex.

An in-vitro study conducted by researchers at Duke and Brown universities resulted in one of the few studies to characterize the role of glycoprotein lubricin molecules — a synovial fluid constituent — in mediating cartilage wear.

A new antimicrobial surface developed by researchers at the University of New Mexico is potentially inhospitable to methicillin-resistant Staphylococcus aureus but safe for humans and animals, according to a recent presentation at the American Vacuum Society 57th International Symposium & Exhibition in Albuquerque.

A 6-week course of teriparatide, in conjunction with periodontal surgery, was associated with a greater resolution of osseous defects in patients with periodontal disease than placebo, according to the results of a Level 1 trial.

The first patient to be treated in an embryonic stem cell phase 1 clinical trial was enrolled at the Shepherd Center in Atlanta and received an investigational drug to treat an acute spinal cord injury, according to a press release from Geron Corporation, which is conducting the FDA-approved study.

Patients with X-ray evidence of knee osteoarthritis who inherited a specific pattern of genetic variations in the interleukin-1 receptor antagonist gene were almost twice as likely as other patients to progress to severe osteoarthritis, according to a recent study.

Several studies show higher rates of heterotopic ossification following combat wounds than civilian injuries. Further highlighting the uniqueness of this abnormal bone regeneration among wounded warriors, a study performed by the United States Navy detected a markedly increased number and proliferative capacity of muscle-derived mesenchymal stem cells in combat wounds compared to uninjured muscle.

Investigators in Japan may have identified at least part of the age-related switch in cell type generation that leads to osteoporosis in an aging population.

Titanium foam could soon be used to replace injured bones with greater effectiveness than the current generation of titanium implants, according to investigators in Dresden, Germany.

The genetic variant 677C>T — a single nucleotide polymorphism that is related to Alzheimer’s disease and cardiovascular disease — has been linked to osteoporotic vertebral fractures, according to scientists from the University of Barcelona.