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Biologics News
New study will use dual approach to find mutations in osteosarcoma
A new United Kingdom-based osteosarcoma study will use advances in genomic research and analysis to identify genes that give rise to the condition — as well as create personalized blood tests for children and young adults. Results of the study, according to the Wellcome Trust Sanger Institute press release, may assist physicians in improving osteosarcoma treatment and the creation of improved methods in the measurement of disease regression.
Stem cell treatment may offer option for non-union fractures
The transplantation of adult stem cells enriched with regenerative hormone insulin-like growth factor may help mend non-union fractures, according to a study from researchers at the University of North Carolina at Chapel Hill School of Medicine.
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Injectable gel may be beneficial in the treatment of arthritis
Investigators at Brigham and Women’s Hospital have constructed an injectable gel that may provide relief for arthritis patients through the targeted release of medicine.
No benefit of platelet-rich plasma found for rotator cuff healing
SAN FRANCISCO — Using autologous platelet-rich plasma at the time of rotator cuff repair fails to have a significant positive impact on healing time as determined by ultrasound observation, according to a study presented here.
New test shows promise for detecting warning signs of joint replacement failure
Investigators at the University of Nebraska Medical Center have developed a test that could be used in detecting the early stages of a major cause of failure in joint replacement implants, according to an American Chemical Society press release.
Study finds demineralized bone matrix potentially helpful in implant fixation
Canadian researchers have found demineralized bone matrix to have osteoinductive capacity in orthotopic bone sites, meaning it could potentially be of use for enhancing implant fixation in revision arthroplasty.
First new lupus drug approved by FDA in more than 50 years
The FDA has approved belimumab to treat patients with active, autoantibody-positive lupus —systemic lupus erythematosus — who are receiving standard therapy, including corticosteroids, antimalarials, immunosuppressives and NSAIDs, according to an FDA press release.
Biomarker could make diagnosing knee injury easier, less costly
A recently discovered fibronectic-aggrecan complex biomarker could assist in the diagnosis of meniscal injury, according to a study published in the Journal of Bone and Joint Surgery.
Combination of growth factors found superior to single growth factor for tendon healing
A mix of growth factors and cytokines in activated serum yields tendon healing superior to single growth factors, with growth factors BMP-12 and TGF-beta yielding better results and more favorable collagen expression ratios respectively.
No complications reported using rhBMP-2 in lumbar fusions with dural tears
ORLANDO, Fla. — Investigators at the Norton Leatherman Spine Center in Louisville, Ky., confirmed in a comparative human study what some preclinical studies have only suggested before now, that using a recombinant human bone morphogenetic protein to foster lumbar fusion in cases where dural tears occur does not affect short-term recovery from the event.