Biologics News

Researchers with the Wellcome Trust Sanger Institute have discovered a new gene associated with osteoarthritis — the third to be identified as having such an association, according to a study published in the American Journal of Human Genetics.

Researchers have discovered a molecular process by which the body can defend against the effects of Clostridium difficile infection, according to a study published online in Nature Medicine.

Researchers at the Rensselaer Polytechnic Institute have developed a technique that allows them to collect large amounts of biochemical information from nanoscale bone samples — potentially allowing for new insights into the fight against osteoporosis and opening a proteomics-based approach to analyzing bone quality.

Erythromycin administered directly at the site of bone breakdown — rather than taken orally — can help prevent and treat bone wear without resulting in long-term whole-body side effects, according to a study published in the August issue of Clinical Orthopaedics and Related Research.

A study from Northwestern University and the University of Pennsylvania has found a neuropeptide in the brain called Substance P appears to trigger heterotopic ossification.

Cornell University engineers have created a biologically based spinal implant that could potentially aid in the relief of back and neck pain, according to a university press release.

A study from Sahlgrenska Academy in the University of Gothenburg, Sweden, has shown that physical exercise can have a positive impact on the formation of cells in the intervertebral discs.

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The intraoperative application of platelet-rich plasma during total knee arthroplasty does not reduce postoperative bleeding, according to researchers in Philadelphia.

Researchers in the United Kingdom have identified genetics, obesity and degree of lumbar disc degeneration as assessed by MRI as the main risk factors for severe or disabling low back pain in women.