Biologics News

iliac crest bone In a prospective, randomized, single-blind study, the amount of pain reported at 6 weeks and 2 years after posterior iliac crest bone harvest by adult patients who needed bone grafting for a spine fusion was comparable regardless of whether they had their iliac crest defect backfilled with a hydroxyapatite-calcium triphosphate biphasic compound.

One injection with 10-times the normal concentration of leukocyte-free platelet-rich plasma is as effective as two injections of platelet-rich plasma for patients with knee osteoarthritis, according to results of a recently published study.

There are several articular cartilage repair techniques being used, including microfracture, autologous chondrocyte implantation and mosaicplasty, and orthopaedic surgeons have found they offer some improvement for patients, overall.

In what areas do you see stem cell therapy being applied in orthopaedics and musculoskeletal medicine in this decade?

Osteochondritis dissecans is an idiopathic lesion of the subchondral bone characterized by osseous resorption, collapse and sequestrum with possible involvement of the articular cartilage. Most frequently it involves the medial femoral condyle (70%), the lateral femoral condyle (20%), the patella (5% to 10%) and the trochlea (<1%). The etiology remains unclear; however, endocrine disorders, familial predisposition, vascular insufficiency, epiphyseal abnormalities and repetitive trauma have been investigated as concurrent causal factors.

One injection with 10-times the normal concentration of leukocyte-free platelet-rich plasma is as effective as two injections of platelet-rich plasma for patients with knee osteoarthritis, according to results recently published in The American Journal of Sports Medicine.

Patients with rheumatoid arthritis showed improvement after anti-tumor necrosis factor therapy, but residual local symptoms suggested there is a higher incidence of joint destruction progression.

Bonesupport announced that Cerament|G has received CE mark for the promotion and protection of bone healing being jeopardized by infection.

Researchers from Hospital for Special Surgery found improved pain and function scores for patients with knee osteoarthritis at 1-year follow-up when treated with platelet-rich plasma.

A new report by Millennium Research Group forecasts “moderate” growth in the global market for hyaluronic acid viscosupplementation to nearly $2.5 billion by 2017 and points to increases in patients with osteoarthritis and obesity as a factor of this growth.