Biologics News

Orthopedics Today features eight stories and videos of importance to emerge from the Impact of Sports 2014 Summit and the American Society for Surgery of the Hand Annual Meeting.

LYON, France — Two groups of patients who underwent 1-level or 2-level transforaminal lumbar interbody fusion with either autologous iliac crest bone or an equal amount of local bone mixed with synthetic hydroxylapatite achieved similar clinical and radiographic outcomes through the 12-month follow-up, according to data presented here.

Cedars-Sinai Health System announced the finalization of an affiliation agreement between Cedars-Sinai, the Kerlan-Jobe Orthopaedic Clinic and Santa Monica Orthopaedic and Sports Medicine Group.

Despite the inclusion of patients with systemic inflammatory disease and those receiving antibiotic treatment, the combined measurement of synovial fluid alpha-defensin and C-reactive protein levels correctly diagnosed 99% of periprosthetic joint infection cases as aseptic or infected, according to study results.

Recently published data have shown autologous chondrocyte implantation may be of benefit in the treatment of articular knee cartilage lesions over the long term.  

Zimmer Holdings Inc. announced that it has acquired ETEX Holdings Inc. of Cambridge, Mass.

Integra LifeSciences Holdings Corporation recently announced several changes to the leadership of its Orthopedics and Tissue Technologies business.

In recent years, there has been increasing interest in strategies to augment the biology of soft tissue healing. Improved understanding of the cellular and molecular mechanisms of tissue degeneration and the limitations in healing and regeneration of musculoskeletal connective tissues have suggested the need for approaches to augment the basic biology of tissue repair. Advances in the understanding of stem cell biology, the role of cytokines and inflammatory mediators in tissue healing and degeneration, gene transfer techniques and the discovery of novel biomaterials suggest tremendous potential to augment the biology of soft tissue repair. The challenge is to continue well-designed translational research studies to bring these techniques to clinical fruition.

DSM announced recently the launch of its new product, Dyneema Purity Radiopaque Fiber.

CHICAGO — Matrix-induced autologous implantation was shown to produce positive long-term outcomes in treating patients with osteochondral defects of the talus, according to data presented at the International Federation of Foot & Ankle Societies Triennial Meeting.