VIDEO: More research required to identify PRP dosage, mechanism of action
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Key takeaways:
- Identifying the dosage of platelet-rich plasma has been a hot topic among orthopedists.
- Research on platelet counts may progress the validation of platelet-rich plasma for multiple orthopedic conditions.
NEW ORLEANS — In this video, Shane A. Shapiro, MD, discusses characterizing, dosing and investigating therapeutic mechanisms of action of platelet-rich plasma.
While PRP has been found to be effective for relieving pain from knee arthritis and restoring function and strength of common tendinopathies, Shapiro said the therapeutic mechanism of action that helps relieve pain or restore function and how often PRP needs to be used are not understood.
“A hot topic is characterizing platelet-rich plasma, counting platelets and investigating the therapeutic mechanism of action,” Shapiro, co-chair of the Biologic Association and sports medicine physician in the department of orthopedic surgery at the Mayo Clinic in Florida, told Healio. “Once we’ve done that, then we will be better at designing clinical trials to look specifically at how often we should be performing such a procedure and what should the minimum requirements be for the products that we use in that procedure.”
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