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September 28, 2021
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VIDEO: Dexamethasone linked with reduced pain, nausea after shoulder arthroplasty

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SAN DIEGO — In this video from the AAOS Annual Meeting, Elizabeth A. Klag, MD, speaks about a prospective, randomized controlled trial of preoperative dexamethasone used in patients undergoing shoulder arthroplasty.

The study included 90 patients undergoing either primary anatomic or reverse shoulder arthroplasty who were randomized to receive either 10-mg IV dexamethasone within 90 minutes prior to surgery or no dexamethasone. Primary outcomes were VAS pain scores in the 24 hours after surgery, as well as anti-emetic use and morphine-equivalent use.

“Our findings were significant for showing overall decreased pain scores in the dexamethasone group for the first 24 hours. We also found significantly lower morphine-equivalent requirements in the dexamethasone group for the first 24 hours,” Klag told Healio Orthopedics.