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August 24, 2021
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Osseointegration may yield improvements for patients with transtibial amputations

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Results presented at the Limb Lengthening and Reconstruction Society Annual Scientific Meeting showed use of osseointegration may lead to subjective and objective improvements in patients with transtibial amputations.

Perspective from S. Robert Rozbruch, MD

Munjed Al Muderis, MB, ChB, and colleagues preoperatively and postoperatively collected SF-36 and modified questionnaire for persons with a transfemoral amputation surveys, physician examinations, and timed up-and-go (TUG) and 6-minute walk tests among 91 patients who underwent 102 consecutive, primary transtibial osseointegration procedures.

In his presentation, Al Muderis noted most patients who underwent transtibial osseointegration experienced an increase in prosthesis use, K-levels and improvement in SF-36 psychological scores. He added most patients also had improvements in the 6-minute walk test, but had a decrease in the TUG test.

Munjed Al Muderis
Munjed Al Muderis

“When we look at the complication rate, we do have 27 infections and we do have at least 35 cases of unplanned surgery,” Al Muderis said in his presentation, which received a second-place award from the Limb Lengthening and Reconstruction Society.

Among 17 implants that were removed, Al Muderis noted 14 were reimplanted. Despite a significantly higher complication rate in transtibial osseointegration compared with transfemoral osseointegration, Al Muderis said patients who underwent transtibial osseointegration had improved performance compared with patients who had a socket prosthesis.

“The implication of a successful outcome from osseointegration surgery, in general, and transtibial osseointegration surgery, in particular, can benefit the overall wider community of orthopedics, as well as surgery in the broader medical field,” Al Muderis, professor of orthopedics at Macquarie University in Sydney, told Healio Orthopedics. “With finding a happy medium between the soft tissue and the implant and the connection through the skin with bacterial colonization that does not cause infection, this can provide a major source for research and explore potential translation of this area of happy medium to other applications in medicine.”