Ropivacaine shows ‘clear advantage’ vs bupivacaine for spinal anesthesia during THA
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Compared with bupivacaine, patients who had ropivacaine had superior ambulation time and distance, quicker post-anesthesia care unit transition and a similar complication rate during total hip arthroplasty, according to published results.
Researchers from Saint Francis Hospital and Medical Center in Hartford, Connecticut, retrospectively reviewed data on 503 patients who received either ropivacaine (ROPI, n = 227) or bupivacaine (BUPI, n = 276) spinal anesthesia for primary unilateral THA.
Outcome measures included postoperative ambulation time and distance, post-anesthesia care unit (PACU) transition time and complications, according to the study.
Researchers found patients who received BUPI had a mean PACU duration of 205 minutes, a mean operative time of 112.2 minutes and a mean time to first ambulation of 11.2 hours. In comparison, patients who received ROPI had a mean PACU duration of 158.4 minutes, a mean operative time of 105.1 minutes and a mean time to first ambulation of 12.9 hours. Researchers also noted similar complications in both cohorts.
“The principal findings of this study centered around the expected response from a short-acting local anesthetic. Ambulation times were significantly better, and ambulation distances showed clinically important improvement with ROPI use,” the researchers wrote in the study. “Ropivacaine shows a clear advantage over bupivacaine for spinal anesthesia during THA when considering rapid recovery,” they added.
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