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June 30, 2020
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PRP shows no improvement for nonoperatively treated Achilles tendon ruptures

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Platelet-rich plasma injections did not show any clinical or functional improvement in the recovery of nonoperatively treated acute Achilles tendon ruptures, according to published results.

Researchers followed 38 men with Achilles tendon ruptures (ATRs) for 12 months, administering four platelet-rich plasma injections (PRP) to the PRP group and four placebo injections to the control group. Both groups were given their respective injections 14 days apart and received congruent exercise programs, which started at 9 weeks after operation, according to the study abstract.

Both groups improved similarly in mean Achilles tendon total rupture score and showed no differences in functional outcomes, the researchers wrote in the study.

“It seems that treatment with multiple PRP injections in nonsurgically treated ATRs did not stimulate healing or improve function and activity levels compared with placebo,” the researchers concluded.