September 25, 2016
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Study reveals rate of death, reoperation after treatment of periprosthetic femur fractures

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Recently published results showed a 24% risk of death or reoperation 1 year following surgical treatment of periprosthetic femur fractures.

Researchers performed a retrospective review of 291 patients treated surgically for periprosthetic femur fractures between 2003 and 2013. Primary outcomes included death and reoperation, according to results.

At 1 year, results showed a 24% chance of either death or reoperation, with a mortality rate of 13.1% and a reoperation rate of 12%. Patients who underwent knee surgery experienced a higher risk of either death or reoperation vs. patients who underwent hip surgery (33% vs. 25%). During a range of follow-up from 1 year to 10 years, researchers found a rate of mortality of 32.3% and risk of reoperation of 16.8%.

Researchers noted a higher mortality and reoperation rate at 1 year among women compared with men and found higher mortality and reoperation rates at 1 year among patients treated with open reduction and internal fixation compared with patients who had a revision. According to results, a significantly lower risk of death but a higher risk of reoperation was found among patients younger than the median age of 78 years. Cox proportional hazard model showed a statistically significantly lower hazard of death and a 14% higher hazard of revision among patients younger than 65 years at the time of surgery.

While patients who underwent total joint arthroplasty fewer than 53 months before they experienced a periprosthetic femur fracture had a significantly lower risk of reoperation, researchers noted these patients had an increased risk of death at 1 year compared with patients who had a longer follow-up after total joint arthroplasty. – by Casey Tingle

 

Disclosures: Drew is a paid consultant for DePuy. Please see the full study for a list of all other authors’ relevant financial disclosures.