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Study: PRP does not halt tunnel widening after ACL reconstruction
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Platelet-rich plasma did not significantly effectively prevent tunnel widening after ACL reconstruction based on results of this randomized clinical trial.
The investigators introduced platelet-rich plasma (PRP) perioperatively in 25 patients undergoing ACL reconstruction with a hamstring graft and compared the results to 25 control patients having the same surgery but without added PRP, according to the abstract.
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At 3 postoperative months, all the patients’ knees were pain-free, stable and had good range of movement. There was slightly less tunnel widening in the PRP group seen on measurements made of the CT scans done at various postoperative timepoints. This difference, however, was not statistically significant. Investigators also found no significant difference between the size of the femoral opening and mid-tunnel or between the size of the tibial opening and mid-tunnel, according to the abstract.
Disclosure: The authors have no relevant financial disclosures.
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