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Decreased need for transfusions in periacetabular osteotomy cases seen with TXA
Results from this retrospective review showed the use of intravenous tranexamic acid during periacetabular osteotomy was linked to a decrease in transfusion requirements and was not associated with an increased risk of thromboembolic disease.
Researchers identified 137 patients (150 hips) who underwent Bernese periacetabular osteotomy, of which 68 patients (75 hips) were treated with intravenous tranexamic acid (TXA) both at the time of the incision and wound closure and 69 patients (75 hips) did not receive antifibrinolytic medication. Investigators compared the need for allogeneic and autologous transfusions between the groups. They also collected postoperative hemoglobin levels, operative times and rates of thromboembolic disease occurring within 6 weeks of surgery.
Results showed the TXA group had no allogeneic transfusions compared with 21% of patients in the control group. Investigators noted no differences between the groups with regard to autologous cell salvage requirements. The risk of venous thromboembolic disease or arterial thromboembolic disease events was not significantly different between the groups, according to researchers. ‒ by Monica Jaramillo
Disclosures: Bryan reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.