Similar results seen for ACL reconstruction with autograft, hybrid graft

Satisfactory and similar subjective and objective clinical outcomes were reported in a study of patients who underwent primary ACL reconstruction with either hybrid graft or autograft.

Researchers prospectively compared 102 patients who underwent primary ACL reconstruction with hybrid graft, autograft or γ-irradiated allograft in a randomized, controlled trial. All patients underwent the same rehabilitation program. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels preoperatively were calculated 1 day, 3 days, 7 days, 14 days, 21 days and 24 days after surgery. The minimum follow-up was 5 years.

The Lachman test and pivot-shift test was used for the knee laxity examination. Senior physicians evaluated clinical outcomes twice preoperatively, as well as at each follow-up using the Lysholm score, Tegner Activity Scale and IKDC (subjective and objective).

At the 5-year follow-up, there were 32 patients in the autograft group, 32 patients in the γ- irradiated group and 31 patients in the hybrid graft group. In all three groups, ESR and CRP values increased. CRP and ESR values increased at 1 day postoperative, CRP reached peak value after 3 days and ESR reached peak value at 7 days postoperative.

At 3 days, 7 days, and 14 days, the γ-irradiated group had significantly higher ESR and CRP values compared with the other groups. Lachman and pivot-shift test results significantly improved from preoperatively to final follow-up; however the groups’ results were not significantly different, according to the findings.

KT-1000 measurements showed the hybrid graft group had slightly superior stability for anteroposterior knee laxity vs. the autograft group, but the difference was not statistically significant. The groups were also no different with regards to Lysholm score, IKDC and Tegner Activity Scale scores. ‒ by Monica Jaramillo

Disclosures: The researchers report no relevant financial disclosures.

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Source:

Li J, et al. Arthroscopy. 2015;doi:10.1016/j.arthro.2015.02.033.