August 20, 2015
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Benzoyl peroxide may reduce P. acnes infection following surgery

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Use of benzoyl peroxide on the skin prior to and following surgery effectively reduced Propionibacterium acnes infection, according to study results.

Forty-eight hours prior to surgery, 50 patients undergoing first-time arthroscopic shoulder surgery were treated with topical 5% benzoyl peroxide cream. Researchers obtained 13 samples per patient following skin preparation and held the cultures for 14 days.

Overall, the researchers obtained 650 culture specimens. Results showed 6% of cases were positive for Propionibacterium acnes at the initiation of surgery. The researchers also found 6% of tissue samples were positive for P. acnes.

Paul Sethi

At the end of surgery, 10% of skin samples were positive for P. acnes, according to study results. The researchers found no difference between the rates of positive culture vs. a 4% rate observed with a control swab. – by Casey Tingle

Disclosure: Sabetta reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.