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Estrogen and dietary silicon are postively correlated with bone health in premenopausal women
Macdonald H. Bone. 2011. doi:10.1016/j.bone.2011.11.020.
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Dietary silicon is positively associated with bone mineral density in premenopausal women, according to recent research published in the Bone journal.
Researchers measured urinary markers of bone resorption and bone formation serum markers in the lumbar spine and femoral neck in 3,198 women between 50 years and 62 years old. According to the abstract, 1,170 of the participants currently used hormone replacement therapy and 1,018 women never used the therapy.
The quartile of energy-adjusted dietary silicon intake was negatively associated with the bone resorption markers but positively associated with serum markers of bone formation. Researchers found a significant correlation between energy-adjusted silicon intake in the femoral neck and estrogen after adjusting for confounders. In addition, the mean femoral neck bone mineral density was “2% lower in the lowest quartile compared to the top quartile of energy-adjusted silicon intake,” the authors wrote.
The authors concluded that while the dietary silicon correlation was present in premenopausal women, postmenopausal women were not affected.