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Study: Low MK incidence found with corneal reshaping
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A recently published study found that the risk of microbial keratitis associated with overnight corneal reshaping contact lenses is similar to that of other overnight modalities.
From a sample of 1,317 patients (640 adults, 677 children) representing 2,599 patient-years of wear, eight events of corneal infiltrates associated with a painful red eye were reported, with six occurring in children and two in adults. Two of the eight events were classified as microbial keratitis (MK) and occurred in children; however, neither resulted in visual acuity loss.
Overall, the estimated incidence of MK was found to be 7.7 per 10,000 years of wear. Estimated incidence was higher in children (13.9 per 10,000 patient-years) than in adults (0 per 10,000 patient-years).
“The risk of MK with overnight corneal reshaping contact lenses is similar to that with other overnight modalities,” Bullimore and colleagues concluded. “The fact that the confidence intervals for the rates estimated overlap should not be interpreted as evidence of no difference. True differences fewer than 50 cases per 10,000 patient-years were beyond the study’s power of detection.”
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