Pediatrics Strabismus News

Elevated episcleral venous pressure has a significant effect on the development and progression of Sturge-Weber syndrome glaucoma in pediatric patients, according to a study.

Axial length may be related to cycloplegic refraction and keratometry in hyperopic non-amblyopic and amblyopic eyes, according to a study.

Elevated serum levels of bevacizumab and reduced serum levels of VEGF were identified in infants with retinopathy of prematurity who underwent intravitreal bevacizumab injections, a study found. “The results suggest that bevacizumab escapes from the vitreous into systemic circulation and could suppress the VEGF concentration in infants with ROP after intravitreal bevacizumab,” the study authors said. “Although no systemic adverse events were observed in our patients, continued extensive evaluation of infants is warranted for possible effects after intravitreal bevacizumab in ROP patients.” The study included 11 infants with highly vascular-active ROP who received unilateral or bilateral 0.25 mg or 0.5 mg intravitreal injections of Avastin (bevacizumab, Genentech) and underwent 23-gauge pars plicata vitrectomy without a cannula. Mean gestational age was 25 weeks. Surgery was performed within 1 week after the injection when deemed necessary. Blood samples were collected before injection and 1 day, 1 week and 2 weeks after injection. Enzyme-linked immunosorbent assays were used to measure serum concentrations of bevacizumab and VEGF. Study results showed a significant negative correlation between the serum concentration of bevacizumab and VEGF in infants who received 0.25 mg or 0.5 mg injections of bevacizumab (P = .0125). Serum levels of bevacizumab were markedly elevated 1 week after a total of 0.5 mg or 1 mg injections. The highest serum level of bevacizumab was identified 2 weeks after a total of 0.5 mg injections, the authors said.

Elevated serum levels of bevacizumab and reduced serum levels of VEGF were identified in infants with retinopathy of prematurity who underwent intravitreal bevacizumab injections, a study found.

SAN ANTONIO — One of the main causes of uveitis is glaucoma, and goniotomy or drainage device implantation can successfully manage pediatric cases that are refractory to medical management and preserve vision, a presenter said here.

SAN ANTONIO — Trabeculotomy can reduce IOP in select cases of aphakic glaucoma and juvenile open-angle glaucoma, a speaker said here.

SAN ANTONIO — Amblyopia is a complex and enigmatic condition driven by neurologic changes in early life, a speaker said here.

SAN ANTONIO — Combined secondary IOL placement with endocyclophotocoagulation is a novel approach to treating a subset of patients with aphakia, glaucoma and an inability to tolerate aphakic contact lenses or spectacles, according to a presentation here.

SAN ANTONIO — In adopting electronic health records, there are challenges for pediatric ophthalmology that other subspecialties do not face, a speaker said here.

SAN ANTONIO — In addition to the traditional recession-resection procedure to treat horizontal sensory strabismus, single-muscle recession may be effective, particularly for deviations of 30 ∆D or less, according to researchers here.