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Ocular Oncology News
Sub-RPE infiltration in vitreoretinal lymphoma patients correlated with shorter survival time
PHILADELPHIA — Vitreoretinal lymphoma patients with subretinal pigment epithelial infiltration had a shorter survival time while those who were younger than 55 years had a longer survival rate, a study found.
Provectus ocular melanoma treatment gets orphan drug designation
The FDA has granted an orphan drug designation to PV-10, Provectus BioPharmaceuticals’ ocular melanoma treatment candidate, according to a press release.
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No survival rate improvement seen after cranio-orbital resection for lacrimal gland carcinoma
Local resection with radiotherapy has comparable results with cranio-orbital resection in terms of tumor recurrence and survival rate in patients with lacrimal gland carcinoma. Therefore, this method should be preferred because it is less disfiguring and preserves useful vision, according to a study.
Woman presents with blurred vision 1 year after cataract surgery
A 65-year-old retired grocery store clerk was referred to the New England Eye Center with more than a year of progressive vision loss in the right eye. Two and a half years before presentation, she underwent uncomplicated cataract surgery on the right eye. Her vision was excellent immediately after the surgery. However, 1 year after the surgery, a “smudge” began obscuring the central vision in the right eye. Over the subsequent year, exams by outside providers revealed only scattered drusen. Yet, the vision continued to decline to the point that she felt that she was “looking through a dense film.” In addition to the declining acuity, the patient also noticed new floaters. She denied any flashes or photophobia.
Younger patients with high-risk melanoma benefit from adjuvant Sutent
CHICAGO — Sunitinib in the adjuvant setting is associated with greater overall survival in high-risk patients with uveal melanoma, especially younger patients, according to a speaker here.
Young woman presents with binocular diplopia and pain with extraocular movements
A 28-year-old woman presented to the Lahey Eye Clinic reporting a 1-week history of constant binocular, horizontal diplopia. In addition to the diplopia, she described pain with extraocular movements and an associated frontal headache. She denied any blurred vision.
Early study results positive for AU-011 in patients with choroidal melanoma
VANCOUVER, British Columbia — A phase 1b/2 clinical trial of AU-011, a light-activated, vision-sparing, tumor cell selective therapy for patients with choroidal melanoma, showed the treatment was safe and resulted in no vision loss for up to 12 months, according to a speaker here.
Man presents with enlarging mass inside right eyelid
A 39-year-old man presented to the New England Eye Center with a slowly enlarging mass in the right eye that had become more noticeable over the past 2 weeks. His complete ocular and systemic review of systems was negative, including recent trauma, headache, sinus congestion, recent illness, fever, night sweats or unintended weight loss. His ocular history was notable for allergic conjunctivitis for which he used over-the-counter antihistamine drops as needed. He had no other significant medical or surgical history. His family history was noncontributory. He did not regularly use any systemic medications. He denied tobacco and recreational drug use and reported occasional alcohol use.
Choroidal melanoma treatment shows promising early results in phase 1b/2 trial
Light-activated AU-011 for the treatment of primary choroidal melanoma was well tolerated with no severe adverse events, while showing promising early efficacy results, in a phase 1b/2 trial, Aura Biosciences announced in a press release.
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Headline News
Burnout, withdrawal remain ‘alarmingly high’ among physicians and residents
September 17, 20242 min read -
Headline News
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September 18, 20242 min read -
Headline News
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September 19, 20242 min read