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Ocular Oncology News
Germline mutation risk with solitary unilateral blastoma may be higher in younger children
NEW ORLEANS — Older age at presentation may be associated with a significantly decreased risk for germline mutation in children with solitary unilateral retinoblastoma, according to a presenter here.
ctDNA reduction after tebentafusp predicts OS in uveal melanoma
Reduction in circulating tumor DNA appeared correlated with longer OS among patients with previously treated metastatic uveal melanoma who received tebentafusp, according to study results presented at the virtual ESMO Congress.
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UCLA researchers receive $1 million to develop novel CAR T-cell therapies for melanoma
Cristina Puig-Saus, PhD, and Daniel S. Shin, MD, PhD, of UCLA Jonsson Comprehensive Cancer Center received a $1 million award from the U.S. Department of Defense for research into novel cell therapies for rare melanomas.
FDA grants priority review to tebentafusp for metastatic uveal melanoma
The FDA granted priority review to tebentafusp for treatment of adults with HLA-A*02:01-positive metastatic uveal melanoma.
Man experiences acute unilateral loss of vision
A 68-year-old man was referred to the New England Eye Center neuro-ophthalmology clinic for evaluation of acute loss of vision in the left eye.
Man presents with daily headaches and blurry vision
A 39-year-old man presented to the comprehensive ophthalmology service at the New England Eye Center with 6 weeks of daily headaches and blurry vision.
Radiotherapy may not improve outcomes in uveal melanoma with extraocular extension
There was no significant difference in survival in eyes that underwent enucleation for uveal melanoma with extraocular extension between postoperative orbital external beam radiotherapy vs. observation, according to a poster presentation.
Woman presents with vision changes, orbital mass
A 43-year-old stay-at-home mom was referred to the Tufts New England Eye Center for a newly identified orbital mass and vision changes in her right eye.
Chemotherapy may offer alternative to enucleation in certain retinoblastoma cases
A conservative approach can be considered as a safe alternative to primary enucleation in children with advanced retinoblastoma in some cases, according to a presenter.
Young woman presents with conjunctival lesion of right eye
A 26-year-old woman was referred to the Lahey Clinic for evaluation of a recurrent conjunctival lesion of the right eye.
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