Ocular Oncology News

The U.S. Food and Drug Administration has granted orphan drug designation to Icon Bioscience for melphalan intraocular injection, its investigational product for treatment of retinoblastoma, according to a company news release.

The direct costs of retinoblastoma treatment pose acute economic stress on families in China, according to a study.

CHICAGO — Novel and advanced technologies are critical for the evaluation and management of patients with ocular malignancies, a speaker said here.

Tarsal tumor location, positive surgical margins and other factors were associated with an increased risk of recurrence of ocular surface squamous neoplasia after surgical resection, according to a study.

Combined use of carboplatin, topotecan and melphalan in selective intra-arterial chemotherapy successfully rescued eyes with intraocular retinoblastoma after failure of intravenous chemotherapy and/or selective intra-arterial chemotherapy with a single or double agent, according to a study.

Failure to detect or correctly diagnose uveal melanoma may delay treatment and increase the need for enucleation, according to a large study.

Baerveldt shunts reduced IOP in eyes that underwent previous anterior segment irradiation for anterior uveal melanoma, according to a study.

Class 2 uveal melanomas demonstrated a higher tumor-related mortality rate and were linked to thicker tumors, older patient age and epithelioid pathology, but no definitive clinical markers could be found to differentiate class 1 and class 2 tumors, according to a study.

Use of enhanced depth imaging spectral-domain optical coherence tomography in imaging small choroidal tumors offered improved visualization and revealed characteristics of choroidal melanoma vs. choroidal nevus, according to a study.

The survival rate for children with isolated choroidal invasion of retinoblastoma was high without adjuvant therapy, according to a study.