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Ocular Oncology News
Fine needle aspiration biopsy safe in uveal melanoma
A study carried out at Retina Consultants of Houston and Houston Methodist Hospital confirmed the safety of fine needle aspiration biopsy in patients with uveal melanoma. No tumor cells were found in the scleral tract of the needle or adjacent pars plana when histopathological analysis was performed after enucleation.
Speaker: Consider intraocular tumors before enucleation, evisceration
PHILADELPHIA — Imaging studies should be completed before enucleation or evisceration surgeries to rule out unsuspected tumors, a speaker said at the Wills Eye Conference.
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Fewer malignant conjunctival tumors seen in children
PHILADELPHIA – Conjunctival tumors in children statistically are more often benign than those in adults and can be differentiated by using a set of markers, a speaker said at the Wills Eye Conference.
FDA clears IND application for Aura Biosciences’ AU-011 for ocular melanoma
The FDA has cleared an investigational new drug application for light-activated AU-011 in ocular melanoma, allowing clinical testing to begin, according to a press release from Aura Biosciences.
Study: Conjunctival tumors in children rarely malignant
In a study of cases spanning nearly 40 years, only 3% of conjunctival tumors in children were malignant.
Topotecan-based regimen improves ocular salvage, vision preservation in advanced retinoblastoma
The combination of systemic vincristine, topotecan and carboplatin with aggressive focal therapies improved ocular salvage and preserved vision in patients with advanced retinoblastoma, according to study results published in the Journal of Clinical Oncology.
PUBLICATION EXCLUSIVE: Chemotherapy can suppress inflammatory signs of periocular filariasis
Dirofilaria repens is an endemic parasite in Mediterranean countries that mostly affects animals. Dirofilaria is a genus of the family Onchocercidae of the super family Filarioidea, order Spirurida in the subphylum Nematoda. Rarely, it can infect humans, causing inflammatory subcutaneous swelling. Human ocular dirofilariasis is sporadically reported in different parts of the world. The species affecting humans are D. immitis, D. repens, D. striata, D. tenuis, D. ursi and D. spectans. The most common presentation is an inflammatory swelling of the ocular adnexa. We report a non-inflammatory presentation of dirofilariasis in the lid mimicking as lipoma in a patient on cancer chemotherapy.
Chemotherapy can suppress inflammatory signs of periocular filariasis
Dirofilaria repens is an endemic parasite in Mediterranean countries that mostly affects animals. Dirofilaria is a genus of the family Onchocercidae of the super family Filarioidea, order Spirurida in the subphylum Nematoda. Rarely, it can infect humans, causing inflammatory subcutaneous swelling. Human ocular dirofilariasis is sporadically reported in different parts of the world. The species affecting humans are D. immitis, D. repens, D. striata, D. tenuis, D. ursi and D. spectans. The most common presentation is an inflammatory swelling of the ocular adnexa. We report a non-inflammatory presentation of dirofilariasis in the lid mimicking as lipoma in a patient on cancer chemotherapy.
Addition of intravitreal chemotherapy boosts salvage rate in retinoblastoma
The addition of intravitreal chemotherapy to strategies for treating retinoblastoma represents an improvement in management of the disease, according to a study.
Uveal melanoma treatment improving but metastasis persists
Despite improving treatment, the rate of metastasis of uveal melanoma is not decreasing, possibly due to early micrometastasis of the tumors when they are relatively small, according to J. William Harbour, MD, of Bascom Palmer Eye Institute. At Retina 2016, Harbour presented his thoughts on systemic management of uveal melanoma.
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