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July 23, 2024
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Patients may benefit from early epiretinal membrane peel after PVR repair

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Patients with epiretinal membrane after proliferative vitreoretinopathy repair may benefit from early peeling, according to a study presented at the American Society of Retina Specialists annual meeting.

Sarah Syeda, MD, a fellow at Illinois Retina Associates, and colleagues conducted a retrospective study that included patients who underwent surgery for proliferative vitreoretinopathy (PVR) repair and subsequent or simultaneous epiretinal membrane (ERM) peels. Out of 686 patients, 44 underwent concurrent or subsequent ERM peels, of which 12 were excluded from the final analysis.

Retina
Patients with epiretinal membrane after proliferative vitreoretinopathy repair may benefit from early peeling, according to a study presented at the American Society of Retina Specialists annual meeting.
Image: Adobe Stock

Of 32 eyes of 32 patients, 56% had stage 4 ERMs, 28% had stage 3, 9% had stage 2 and 6% had stage 1.

Syeda said visual acuity improved most significantly in patients with stage 4 ERMs. These patients went from a visual acuity of 20/1000 before peel to 20/395 at final follow-up. Patients in the stage 3 and 2 groups also experienced visual acuity improvement after ERM peel.

Across all groups, the ERMs formed about 2 to 3 months after the initial PVR surgery. Patients in the stage 4 and 3 groups underwent membrane peel at about 6 months after their initial surgery, while patients in the stage 2 and 1 groups underwent peel at about 13 and 19 months after initial surgery, respectively.

“In those with stage 3 and stage 4 membranes, the timing of peel tended to occur around the time of silicone oil removal, so perhaps delaying the time of peel gave them a worse final visual outcome,” Syeda said. “However, it is still reassuring to see that even though these stage 4 ERMs developed around 2 months after the PVR surgery, peeling them did improve vision.”