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July 03, 2024
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VIDEO: Phase 3 dry AMD trial focuses on protecting photoreceptors

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PARK CITY, Utah — In this Healio Video Perspective from Clinical Trials at the Summit, Reenie McCarthy of Stealth BioTherapeutics discusses a phase 3 clinical trial of elamipretide in dry age-related macular degeneration.

The trial targets a new FDA-approved endpoint of photoreceptor protection, building on promising results from phase 2 clinical trials, McCarthy said.

“By directly protecting the photoreceptors, which we saw was highly associated with improvements in low-light visual acuity with a significant number of patients gaining two or more lines, we think we are getting to the heart of what matters for patients living with this devastating progressive disease,” she said.