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May 16, 2024
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VIDEO: Gene therapy shows promising disease control for wet AMD in clinical trials

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FORT LAUDERDALE, Fla. — In this Healio Video Perspective from the Retina World Congress, Carl D. Regillo, MD, discusses promising results for the Ixo-vec gene therapy for neovascular age-related macular degeneration.

Ixo-vec (ixoberogene soroparvovec, Adverum Biotechnologies), formerly referred to as ADVM-022, is being investigated in both the phase 2 LUNA and phase 1 OPTIC studies.

“We’re seeing better tolerance to this form of intravitreal gene therapy and excellent disease control, and the OPTIC phase 1 extension program is showing ongoing excellent control now out through 3 years,” he said.