VIDEO: Pegcetacoplan efficacious for geographic atrophy; vasculitis reports a concern
SEATTLE — In this video, Esther M. Bowie, MD, discusses research presented at the ASRS meeting on the long-term efficacy of pegcetacoplan as well as late-breaking reports of ocular inflammation associated with the treatment.
“The open-label study basically showed that the pegcetacoplan did decrease geographic atrophy out to month 30,” Bowie, a professor of ophthalmology at the Penn State Health Milton S. Hershey Medical Center, said. “You had a greater decline if you use it monthly vs. every other month.”
However, Bowie noted late-breaking reports of ocular inflammation and vasculitis with vision loss associated with pegcetacoplan use.
“That may affect how we treat these patients,” she said.
Reference:
- Steinle NC. Long-term efficacy of pegcetacoplan in patients with geographic atrophy. Presented at: American Society of Retina Specialists annual meeting; July 28-Aug. 1, 2023; Seattle.
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