May 03, 2022
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VIDEO: Dry eye treatment improves signs, symptoms at 1 week
Issue: June 10, 2022
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DENVER — A large phase 2b study showed that the use of Aerie Pharmaceuticals’ AR-15512 compound resulted in improved tear production and dry eye symptoms at 7 days and 14 days, according to David Wirta, MD, of the Eye Research Foundation.
The TRPM8 cold thermoreceptor agonist affects the receptors on the conjunctiva, cornea and eyelid to stimulate a cold feeling to the eye, leading to reflex tearing, Wirta said.
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Source:
Wirta D, et al. Dry eye sign, symptom and quality of life improvements associated with administration of AR-15512. Presented at: Association for Research in Vision and Ophthalmology meeting; May 1-4, 2022; Denver.
Disclosures:
Wirta reports receiving grant support from Aerie Pharmaceuticals as principal investigator for this study.
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