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May 02, 2022
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Novel ERG method aids in monitoring patients with posterior uveitis

DENVER — A simplified method of electroretinography may aid in monitoring patients with posterior uveitis, according to a presenter here.

“ERGs have been very reliable in detecting retinal function. However, it takes a long time for the patient to do it, around 3 hours,” Ngoc Trong Tuong Than told Healio/OSN at the Association for Research in Vision and Ophthalmology meeting. “We have a new modality, flicker ERG, that takes around 15 minutes for each patient.”

Than and colleagues performed a cross-sectional study of 134 eyes of 85 patients with posterior uveitis who did not have concomitant retinal disease. They collected demographic and clinical data from the patients and performed flicker ERG with the Diopsys Nova.

Fifty-two eyes had retinal vasculitis, and 62 eyes had optic disc inflammation. There was a statistically significant difference in magnitude between the 52 eyes with retinal vasculitis and the 82 eyes without it.

The 13 eyes with diffuse vasculitis had reduced magnitude compared with the 39 eyes that had only peripheral vasculitis (P < .01). No significant difference was observed between eyes with or without optic disc inflammation.

Than said these findings suggest that flicker ERG can also be used as a screening tool to detect if a patient has retinal vasculitis.

“We plan to perform a follow-up study with a larger population, not just posterior uveitis patients,” Than said.