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September 03, 2021
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No predictive risk factors identified for endophthalmitis following pars plana vitrectomy

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Researchers were unable to identify any predictive risk factors for endophthalmitis following pars plana vitrectomy, according to a poster presentation at the Women in Ophthalmology Summer Symposium.

Alexa R. Thibodeau, MD, and colleagues, conducted a retrospective chart review of all cases of endophthalmitis following pars plana vitrectomy at the University of Michigan between January 2012 and December 2020. To be included, cases of acute postoperative endophthalmitis must have been diagnosed following pars plana vitrectomy, conducted either as a solo or combination procedure, researchers wrote. Following identification, all potential risk factors were assessed for their statistical significance.

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Twelve cases were identified with a mean annual rate of 0.185%, researchers wrote.

Indications for the procedure included epiretinal membrane, vitreous hemorrhage, retinal detachment and macular holes. There was no noted trend regarding surgeon, surgical assistant, scrub technician, circulating nurse, operating room or operating time.

“Three surgeons reported no changes in their surgical practice over time to avoid endophthalmitis, but six surgeons cited increased utilization of sutured wound closure and air-fluid exchange, additional betadine swab prep, and careful assessment of wound integrity at the end of PPV,” the authors wrote.

Every case received standard betadine preparation and combination steroid-antibiotic drops postoperatively. The most common organism to cause endophthalmitis was coagulase-negative Staphylococcus, the authors wrote.