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April 27, 2021
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Micropulse transscleral cyclophotocoagulation may lower IOP in pediatric patients

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Micropulse transscleral cyclophotocoagulation lowered IOP in pediatric patients with refractory glaucoma, according to a poster at the virtual American Association for Pediatric Ophthalmology and Strabismus annual meeting.

Researchers conducted a retrospective review of patients with pediatric glaucoma who underwent micropulse transscleral cyclophotocoagulation (CPC). The review included 17 eyes of 16 patients.
Baseline IOP was 33.2 ± 13 mm Hg. After the procedure, average IOP was 25 ± 9.9 mm Hg, with a final follow-up pressure of 24.2 ± 11 mm Hg, according to the poster. The procedure resulted in an average IOP reduction of 8.3 mm Hg (P < .01) compared with preoperative IOP. At final follow-up, the reduction was 9.1 mm Hg (P < .01).

Courtney L. Kraus

“Micropulse is a potentially valuable tool in the management of pediatric glaucoma. It is important to manage the patient’s expectation regarding the treatment, as it doesn’t appear to have the same potential degree of IOP lowering, or possibly duration of effect, as continuous CPC. Quite a few patients had either no or minimal IOP lowering. However, micropulse does provide a valuable tool such as a bridge to other surgical intervention or a treatment option prior to resorting to continuous CPC,” Courtney L. Kraus, MD, and Bo Wang, MD, PhD, two of the poster authors, told Healio/OSN.

There was no hypotony or phthisis noted during the study period.

“Long-term studies are necessary to identify the persistence of this IOP-lowering effect as well as the long-term safety profile in children,” the authors wrote.