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March 22, 2021
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Nose-pivoted drop delivery device improves eye drop accuracy, placement

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Patients using a nose-pivoted drop delivery device experienced improved eye drop delivery and accuracy compared with a traditional eye drop delivery system.

“The aid improved eye drop delivery success, reduced bottle tip contact against the eye and decreased the number of eye drops wasted,” Robert M. Kinast, MD, said at the virtual American Glaucoma Society annual meeting.

Kinast and colleagues evaluated self-administered eye drops in 100 eyes of 50 participants with glaucoma who reported difficulty self-administering drops. A traditional eye drop delivery system was compared with the GentleDrop (Bedo Solutions), a nose-pivoted drop delivery device (NPDD).

Two graders used digital video to review each participant’s eye drop delivery and evaluated accuracy of placement, bottle tip contact with the ocular surface, and number of drops dispensed at baseline and after a standardized teaching session. Primary success was defined as accurate drop placement with no tip contact to the ocular surface, while secondary success was one drop dispensed.

Participants graded their experience using both methods on a scale of 1 to 10, with 10 being the easiest. The mean score for ease of use was higher for the NPDD, 8.9, compared with 6.7 for the baseline traditional device and 7.0 for the post-teaching traditional device. Additionally, 94% of the participants said they preferred using the NPDD over the traditional eye drop delivery system, Kinast said.

Greater than 90% of drops reached the ocular surface with both methods; however, the NPDD bottle tip contacted only 10 eyes compared with 33 eyes with the baseline traditional method (P < .001) and 25 eyes with the post-teaching traditional method (P = .009).

The NPDD resulted in 1.7 drops per use compared with 2.2 drops for the traditional baseline method (P = .017) and 2.4 drops for the post-teaching traditional method (P = .006).

Primary and secondary success was achieved in 86% and 54%, respectively, of participants using the NPDD. This is compared with primary and secondary success of 66% and 28%, respectively, in traditional baseline participants and 70% and 40%, respectively, in post-teaching traditional participants.

“The aid helps subjects who struggled with traditional delivery. Forty-seven of 50 subjects preferred the aid over traditional delivery. Forty-nine would recommend the device to a friend,” Kinast said.