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February 09, 2021
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Intraoperative antibiotic use may lower risk of sling exposure, infection

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Intraoperative antibiotic use during frontalis suspension surgery with a silicone rod sling decreased the risk of sling exposure or infection, according to a study.

“Patients who received silicone rod slings who did not receive intraoperative antibiotics had a significantly higher risk of infection or exposure compared to patients who did receive intraoperative antibiotics,” Christopher R. Dermarkarian, MD, said at the virtual American Society of Ophthalmic Plastic and Reconstructive Surgery annual meeting.

Dermarkarian and colleagues conducted a retrospective study of 164 pediatric patients with ptosis who underwent frontalis suspension surgery at a single center between 2014 and 2019. The aim of the study was to determine preoperative, perioperative or postoperative factors that contribute to frontalis sling infection or exposure.

All patients were younger than 18 years, had at least 30 days of follow-up and received silicone rod, Gore-Tex or autogenous fascia lata slings during surgery.

While there was no difference in rate of infection dependent upon the sling material, there was a statistically significant higher risk of infection or exposure in patients with a silicone rod sling who did not receive intraoperative antibiotics (P = .03).

Other factors considered that were not associated with an increased or decreased risk of sling exposure or infection were age, gender, congenital syndrome, prior antibiotic use, soaking in antibiotic solution, postoperative antibiotics and date of last follow-up visit.

“Antibiotic soaking of silicone rod slings or use of postoperative antibiotics should be limited as there is no change in risk of sling exposure or infection,” Dermarkarian said.